Table 1.
Doxorubicin (μg/mL) | 5-fluorouracil (μg/mL) | Cisplatin (μg/mL) | |
---|---|---|---|
E2F1 | 1.52 ± 0.15* | 5.22 ± 0.13* | 3.52 ± 0.15* |
GFP | 0.53 ± 0.09 | 3.85 ± 1.01 | 2.26 ± 0.38 |
NC | 0.61 ± 0.12 | 4.12 ± 0.72 | 2.52 ± 0.83 |
IC50 values were evaluated by CCK-8 assay. Each experiment was conducted in triplicate. Data are expressed as means ± SD of four independent experiments. One-way analysis of variance followed by Dunnett’s multiple comparison test revealed statistical differences of *P < 0.05 for the E2F1 group versus the GFP group and NC group.