Table 3.
Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for sarcomas with single symptoms and combinations of symptoms and signs that have been defined as inclusion criteria for bone tumors in the Cancer Patient Pathway, in suspected sarcoma patients
| Bone tumors (n = 420) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Sarcoma | Non-sarcoma | Sensitivity | Specificity | PPV | NPV | |||
| Symptom aPresent | (n = 84) | (n = 336) | % (95% CI) | % (95% CI) | % (95% CI) | % (95% CI) | ||
| + | – | + | – | |||||
| 4 | 12 | 72 | 44 | 292 | 14 (8–24) | 87 (83–90) | 21 (12–34) | 80 (76–84) |
| 5 | 69 | 15 | 237 | 99 | 82 (72–90) | 30 (25–35) | 23 (18–28) | 87 (79–92) |
| 4 + 5 | 8 | 76 | 14 | 322 | 9 (4–18) | 96 (93–98) | 36 (17–59) | 81 (77–85) |
a Symptom 4: palpable bone tumor; symptom 5: deep persisting bone pains.