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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Nat Struct Mol Biol. 2014 Nov 10;21(12):1028–1034. doi: 10.1038/nsmb.2914

Fig. 6. Schematic representation of subunit interactions in the human core Mediator complex based on composite data from CX-MS and biochemical approaches.

Fig. 6

Intra-module cross-links in the middle module are in light blue; intra-module cross-links in the head are in brown; MED14 cross-links are in purple; inter-module cross-links between head and middle modules are in dark blue.