Table 2.

Known mutations in ASD for excitatory and inhibitory genes.

Gene type	Symbol	Mutation (residue or genome coordinates, hg18)	Damaging?	Condition	Reference
Excitatory	ELFN1	chr7:1754k-1774k	Loss, exonic	Autism	SFARI, Prasad et al., 2012
Excitatory	GRIK2	chr6:101961k-102006k	Gain, intronic	Autism	SFARI, Prasad et al., 2012
Excitatory	GRIK2	chr6:102425k-102437k	Loss, intronic	Autism	SFARI, Prasad et al., 2012
Excitatory	NRXN1	chr2:50722k-50730k	Loss, exonic	Autism	SFARI, Prasad et al., 2012
Excitatory	NRXN1	chr2:50708k-50721k	Loss, exonic	Autism	SFARI, Prasad et al., 2012
Excitatory	NRXN1	chr2:50421k-50908k	Loss, exonic	Autism	SFARI, Prasad et al., 2012
Excitatory	NRXN1	chr2:50722k-50730k	Loss, intronic	Autism	SFARI, Prasad et al., 2012
Excitatory	NRXN1	chr2:50913k-50958k	Loss, intronic	Autism	SFARI, Prasad et al., 2012
Excitatory	NRXN1	chr2:51045k-51127k	Loss, exonic	Autism	SFARI, Prasad et al., 2012
Excitatory	RELN	p.Q417*	Nonsense	Autism	Neale et al., 2012
Excitatory	SLC6A1	p.A288V	Missense	Autism	Sanders et al., 2012
Excitatory	STXBP1	p.R551C	Missense	Autism	Neale et al., 2012
Inhibitory	CEP112	chr:1761133k-61139k	Loss, intronic	autism	SFARI, Prasad et al., 2012
Inhibitory	GAD1	-	Silent	Autism	O'Roak et al., 2012
Inhibitory	MTMR2	p.N283D	Damaging	Autism	Sanders et al., 2012
Inhibitory	NF1	p.H2459N	Missense predicted tolerated, benign	Autism	Sanders et al., 2012
Inhibitory	NF1	p.A2644V	Missense, predicted probably damaging	Control	Sanders et al., 2012
Inhibitory	NF1	chr17:26493k-26507k	Loss, exonic	Autism	SFARI, Prasad et al., 2012