Table 2.
SLE participant differences: ACR, medications, and 25(OH)D status.
| N = 80 | Number (%) | P value | Number (P value) | Number (P value) |
|---|---|---|---|---|
| Vit. D level | Vit. D deficient | Vit. D insufficient | ||
| Clinical ACR SLE features | ||||
| Malar rash | 57 (71.3) | 0.54 | 16 (0.07) | 31 (0.14) |
| Discoid rash | 3 (3.8) | 0.23 | 2 (0.28) | 1 (1.0) |
| Photosensitivity | 43 (53.8) | 0.52 | 11 (0.07) | 23 (0.38) |
| Oral/nasal ulcers | 29 (36.3) | 0.12 | 10 (1.0) | 12 (0.36) |
| Arthritis | 63 (78.8) | 0.63 | 21 (0.58) | 31 (1.0) |
| Serositis | 20 (25.0) | 0.91 | 6 (0.79) | 10 (1.0) |
| Renal disorder | 37 (46.3) | 0.49 | 16 (0.17) | 15 (0.19) |
| Neurological disorder | 33 (41.3) | 0.67 | 12 (1.0) | 17 (0.82) |
| Haematological disorder | 39 (48.8) | 0.95 | 14 (1.0) | 20 (0.82) |
| Leucopoenia | 18 (22.5) | 0.57 | 7 (0.78) | 10 (0.6) |
| Immunologic disorder | 27 (33.8) | 0.42 | 11 (0.47) | 14 (0.81) |
| Antinuclear antibody ≥1 : 80 | 63 (78.8) | 0.27 | 24 (0.39) | 28 (0.18) |
| Medications | ||||
| Hormones | 30 (37.5) | 0.23 | 5 (0.01) | 16 (0.65) |
| ITM | 67 (83.8) | 0.56 | 20 (0.05) | 36 (0.07) |
| Prednisolone | 34 (42.5) | 0.31 | 7 (0.03) | 21 (0.07) |
| Vitamin D + prednisolone | 15 (18.8) | 0.71 | 4 (0.56) | 9 (0.4) |
Vitamin D categories: deficiency (50 nmol/L (≤20 ng/mL)) and insufficiency (52.5–72.5 nmol/L (>20.0 ≤ 29 ng/mL)) [3].