Table 1.
Physical Properties of Constructs After 4 Weeks of Culture
| Construct composition (SZ:MZ) | Wet weight (mg) | Hydration (%) | Diameter (mm) | Thickness (mm) |
|---|---|---|---|---|
| 0:100 | 32.6±1.4a | 87±2a | 6.2±0.1a | 0.92±0.05a |
| 25:75 | 24.0±3.1b | 85±2a,b | 6.1±0.1b | 0.72±0.06b |
| 50:50 | 17.8±2.4c | 84±2b,c | 5.4±0.1c | 0.66±0.10b |
| 75:25 | 16.9±1.6c | 84±3c | 5.7±0.1c | 0.51±0.06c |
| 100:0 | 9.7±0.5d | 81±3c | 5.3±0.1d | 0.37±0.06d |
The diameter, thickness, wet weight, and hydration of constructs were measured. Construct size and hydration increased with increasing proportion of MZ chondrocytes. Values are presented as mean±SD.
a–d
Within a column, groups not sharing an identical alphabet are significantly different from one another (p<0.05). For each metric, each group was significantly differnt from all others.
MZ, middle zone; SZ, surface zone.