Table 6.

Influence of N^G-Nitro-l-Arginine on Anti-Inflammatory Effect of A. muricata Fruit Extract

		Change in paw circumference (cm)
Treatment	Dose	1 h	2 h	3 h	4 h	5 h	6 h
Vehicle	10 mL/kg	0.73±0.10	1.05±0.03	1.18±0.03	1.23±0.08	1.03±0.08	0.83±0.11
L-NNA	20 mg/kg	0.45±0.13	0.58**±0.12	0.68**±0.12	0.58***±0.09	0.53**±0.08	0.45*±0.09
% Inhibition		37.93	45.24	42.55	53.06	48.78	45.45
L-NNA+AM	20+200 mg/kg	0.40±0.08	0.48***±0.09	0.58***±0.09	0.60***±0.07	0.55**±0.09	0.40**±0.11
% Inhibition		44.83	54.76	51.06	51.02	46.34	51.52

Values are expressed as mean±SEM. Statistical level of significance, ^*P<.05, ^**P<.01, ^***P<.001 as compared with vehicle control–treated using two-way ANOVA followed by Bonferroni post hoc multiple-comparison test. Bold values indicate percentage inhibition of edema.

L-NNA, N^G-nitro-l-arginine.