Table I. Expression of GBM stem–like markers and NK cell ligands.
Ligand/Marker | P3 (% of Cells) | 2011-20-I (% of Cells) | 2012-018 (% of Cells) | P3 (MFI) | 2011-20-I (MFI) | 2012-018 (MFI) |
---|---|---|---|---|---|---|
ULBP-1 | 68.23 | 41 | 33.2 | 23,923 | 36,621 | 19,524 |
ULBP-2/5/6 | 95.22 | 90.18 | 71.2 | 183,413 | 67,147 | 58,897 |
ULBP-3 | 63.03 | 50 | 41.4 | 28,371 | 19,871 | 29,928 |
MICA | 91.03 | 95.16 | 91.65 | 371 | 344 | 234 |
MICB | 6.91 | 13.13 | 41.22 | 11,482 | 43,564 | 13,626 |
HLA-A,B,C | 99.28 | 99.7 | 99.17 | 1,571 | 724 | 9,456 |
HLA-DR,DP,DQ | 0 | 19.5 | 63.42 | 0 | 466 | 900 |
HLA-E | 0 | 0 | 25.2 | 0 | 0 | 415 |
HLA-G | 0 | 0 | 0.1 | 0 | 0 | 971 |
GFAP | 98.8 | 100 | 79.98 | 1,131 | 1,123 | 466 |
Vimentin | 95.6 | 87.6 | 80.4 | 1,399 | 532 | 3,206 |
Nestin | 97.6 | 99.7 | 96.81 | 6,148 | 2,115 | 1,176 |
CD31 | 0 | 0 | 35.23 | 0 | 0 | 677 |
CD133 | 39 | 31.5 | 21.12 | 172 | 102 | 419 |
A2B5 | 42.6 | 77.3 | 40.04 | 250 | 489 | 877 |
CD15 | 0.25 | 0 | 40.72 | 0 | 0 | 679 |
HLA-A3 | — | — | 98.1 | 0 | 0 | 5,584 |
HLA-Bw4 | 97.5 | 77.4 | 97.3 | 2,354 | 621 | 4,802 |
The proportion of specifically stained cells was calculated by subtracting the percentage of isotype-control–positive cells from the percentage of marker-positive cells.
—, HLA-A3 not present on genotype and not expressed on protein level.