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. Author manuscript; available in PMC: 2014 Dec 8.
Published in final edited form as: Inflamm Bowel Dis. 2013 Mar;19(3):471–480. doi: 10.1097/MIB.0b013e31827e78eb

Figure 4.

Figure 4

A.Genes with altered expression upon miR-224 stimulation are involved in the cell cycle control. The list of genes identified to be downregulated upon miR-224 stimulation was filtered and input into Ingenuity Pathway Analysis with the purpose of identifying general mechanisms of miR function. Top associated network functions are displayed. B. In-silico analysis identifies p21 as a putative direct target of miR-224. The list of dysregulated genes identified by cDNA arrays (downregulated and upregulated genes are highlighted in green and red, respectively) was overlayed on the list of Targetscan predicted miR-224 targets.