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. 2014 Dec 8;9(12):e114536. doi: 10.1371/journal.pone.0114536

Figure 3. Postmortem examination by H&E showed PI3K inhibition on bladder wall thickening during cystitis.

Figure 3

Transverse sections (10 µm) of the urinary bladder from control (A), cystitis (B) and cystitis with LY294002 (LY) treatment (C) were stained by H&E (m: muscular layer; u: urothelium; d: bladder dome). The thickness of the bladder wall was increased by cystitis (D). LY294002 treatment reduced bladder wall thickness caused by cystitis (D). Bar  = 200 µm. n = 3. *, p<0.05 vs vehicle control. #, p<0.05 vs CYP cystitis.