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. 2014 Dec 8;9(12):e114652. doi: 10.1371/journal.pone.0114652

Figure 6. Tissue distribution of HSV-2 specific memory T cells following genital HSV-2 infection of guinea pigs.

Figure 6

Hartley guinea pigs were infected ivag with HSV-2 strain MS and lymphocytes isolated from the indicated tissues on days 99-150 post infection. HSV-specific, IFN-γ SCs were detected and quantified by IFN-γ ELISPOT. The frequency of HSV-specific, IFN-γ SC per 106 cells is given in A,C,E,G and the total number of HSV-specific, IFN-γ SC is given in B,D,F,H for each tissue. Each data point represents results from an individual animal. (* P<0.05; ** P<0.01, Student's t test; *** P<0.0001, Chi square).