Table 2: Comparison of the AUC1 and AUC2 scores calculated for 81 intracellular signaling pathways for nine human cancer types basing on the transcriptomic data.
| Cancer type | AUC1 > 0.7a | AUC2 > 0.7b | AUC1/2 > 0.7; AUC1 > AUC2c | AUC1/2 > 0.7; AUC2 > AUC1d | AUC1 > 0.75e | AUC2 > 0.75f | AUC1/2 > 0.75; AUC1 > AUC2g | AUC1/2 > 0.75; AUC2 > AUC1h |
|---|---|---|---|---|---|---|---|---|
| Basal cell carcinoma | 40 | 5 | 40 | 1 | 23 | 0 | 23 | 0 |
| Bladder cancer | 20 | 23 | 15 | 15 | 10 | 9 | 8 | 4 |
| Glioblastoma | 66 | 68 | 66 | 12 | 59 | 5 | 59 | 0 |
| Hepatocellular | 17 | 0 | 17 | 0 | 7 | 0 | 7 | 0 |
| Lung adenocarcinoma | 32 | 2 | 32 | 1 | 21 | 0 | 21 | 0 |
| Oral tongue squamous cell carcinoma | 5 | 0 | 5 | 0 | 2 | 0 | 2 | 0 |
| Primary melanoma | 25 | 0 | 25 | 0 | 13 | 0 | 13 | 0 |
| Prostate cancer | 28 | 8 | 28 | 5 | 16 | 0 | 16 | 0 |
| Renal cancer | 19 | 10 | 19 | 6 | 10 | 0 | 10 | 0 |
a
Number of signaling pathways where AUC1 > 0.7
b
Number of signaling pathways where AUC2 > 0.7
c
Number of signaling pathways where AUC1/2 > 0.7, and AUC1 > AUC2
d
Number of signaling pathways where AUC1/2 > 0.7, and AUC2 > AUC1
e
Number of signaling pathways where AUC1 > 0.75
f
Number of signaling pathways where AUC2 > 0.75
g
Number of signaling pathways where AUC1/2 > 0.75, and AUC1 > AUC2
h
Number of signaling pathways where AUC1/2 > 0.75, and AUC2 > AUC1