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(A.) Engraftment of intracranial tumors was confirmed by serial BLI over the two week post implantation period. (B) A subcutaneous osmotic pump delivered either PBS or POL5551 (low dose or high dose) continuously over 28 days. Mice received either mcr84 or vehicle IgG antibody (10 mg/kg i.p. twice weekly for 4 weeks).
