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. 2014 Sep 9;5(20):9811–9822. doi: 10.18632/oncotarget.2443

Table 1. Drug effects on proliferation and apoptosis in U87 tumors.

Ki67 TUNEL
Treatment Group Fraction1 Pos Neg P-value2 Fraction Pos Neg P-value
PBS and IgG 0.28 567 1477 0.12 242 1793
PBS and mcr 0.24 443 1440 0.0027 0.14 297 1866 0.0794
POL and IgG 0.21 418 1593 0.0001 0.25 290 873 0.0001
POL and mcr 0.21 377 1392 0.0001 0.17 371 1792 0.0001
1

Fraction of Ki67 positive or TUNEL positive cells was calculated as #positive cells/(#positive cells + #negative cells) in multiple high-powered fields from three brains from each treatment group.

2

P values were calculated using a two-tailed Fisher’s exact test to compare treatment groups to control (PBS and IgG).