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. 2014 Sep 8;5(20):9823–9837. doi: 10.18632/oncotarget.2450

Figure 4. PI3K, AKT, NF-kappaB, PTEN, and MMPs were regulated by TM4SF4 expression in A549 cells.

Figure 4

(A) Western blot analysis of levels of phosphorylated or total PI3K, AKT, NF-kappaB, and ERK in siTM4SF4- or pcDNA-TM4SF4–transfected A549 cells. PTEN expression was also analyzed. Beta-actin served as internal control. (B) Western blot analysis of metalloproteinases 2, 7, and 9, N-cadherin, and C-cadherin in siTM4SF4- or pcDNA-TM4SF4–transfected A549 cells. (C) Phosphorylation of EGFR and IGF1R in siTM4SF4- and pcDNA-TM4SF4–transfected A549 cells.