Table 5. Sequence identity of kinases bound by multi-targeted AK inhibitors with AK.
| S. No. | Inhibitor | PDB | UNIPROT identifier | Swiss-prot identifier | Classification (Group/Family/Sub-family) | % Identity* |
| 1. | AT9283 | 2W1G | O14965 | AURKA_HUMAN | Other/Aur | - |
| 2W1H | P24941 | CDK2_HUMAN | CMGC/CDK/CDK2 | 34 | ||
| 2W1I | O60674 | JAK2_HUMAN | TK/JAK | 26 | ||
| 2. | VX-680/MK-0457 | 3E5A, 4JBQ | O14965 | AURKA_HUMAN | Other/Aur | - |
| 3AMB | P17612 | KAPCA_HUMAN | AGC/PKA | 33 | ||
| 2XYN | P42684 | ABL2_HUMAN | TK/ABL | 27 | ||
| 2F4J | P00519 | ABL1_HUMAN | TK/ABL | 27 | ||
| 4B8M | Q6DE08 | AUKBA_XENLA | Other/Aur | 70 | ||
| 4AF3 | Q96GD4 | AURKB_HUMAN | Other/Aur | 74 | ||
| 3. | JNJ-7706621 | 3AMA | P17612 | KAPCA_HUMAN | AGC/PKA | 33 |
| 4. | PHA-739358 | 2J50 | O14965 | AURKA_HUMAN | Other/Aur | - |
| 2V7A | P00519 | ABL1_HUMAN | TK/ABL | 27 | ||
| 5. | YL1-038-31 | 3UO5 | O14965 | AURKA_HUMAN | Other/Aur | - |
| 3UNJ | P24941 | CDK2_HUMAN | CMGC/CDK/CDK2 | 34 | ||
| 6. | YL5-083 | 3UO6 | O14965 | AURKA_HUMAN | Other/Aur | - |
| 3UNK | P24941 | CDK2_HUMAN | CMGC/CDK/CDK2 | 34 |
*A pairwise sequence alignment of AURKA_HUMAN against the individual kinases was done with blast-p to calculate the sequence identity.