Table 2.
Comparison of GRM2−/− and wild-type (WT) mice in the Black & White Alley, the Elevated Plus Maze and Open Field.
| Task & measure | WT | GRM2−/− | Statistics |
|---|---|---|---|
| Black & White Alley | |||
| Total time in white arm (s) | 40.2 ± 2.6 | 37.5 ± 2.8 | t < 1; p > 0.40 |
| Number of crossings | 8.7 ± 0.9 | 8.6 ± 0.8 | t < 1; p > 0.90 |
| Elevated Plus Maze | |||
| % time in open arms | 11.1 ± 1.9 | 12.5 ± 1.9 | t < 1; p > 0.50 |
| Latency to enter open arms (s) | 25.1 (10.6–37.6) | 11.5 (1.7–20.6) | U = 72; p = 0.150 |
| Total distance travelled (cm) | 1410.8 ± 116.4 | 1543.2 ± 101.0 | t < 1; p > 0.40 |
| Number of open arm entries | 9.6 ± 1.3 | 11.1 ± 1.3 | t < 1; p > 0.40 |
| Open Field | |||
| Time in centre (s) | 7.3 ± 0.8 | 5.6 ± 0.5 | t(27) = 1.76; p = 0.089 |
| Latency to enter centre (s) | 28 (24.6–38.5) | 20.2 (6.53–57.4) | U = 78; p = 0.239 |
| Total distance travelled (cm) | 3314.3 ± 155.1 | 3119.2 ± 142.9 | t < 1; p > 0.30 |
Parametric data are presented as mean ± SEM and were analysed with t-tests. Non-parametric data are presented as median (inter-quartile range) and were analysed with Mann–Whitney U-tests. n = 15 WT; n = 14 GRM2−/−.