Table 4.
Comparison of GRM2/3−/− and wild-type (WT) mice in two versions of the Neophagia Test.
| Task & measure | WT | GRM2/3−/− | Statistics |
|---|---|---|---|
| Neophagia I (Milk/Jug) | |||
| Latency to contact (s) | 4 (3–6) | 4 (3–5) | U = 209.5; p = 0.518 |
| Latency to drink (s) | 13 (9.8–17) | 13 (9–16) | U = 198; p = 0.834 |
| Latency to drink – latency to contact (s) | 7 (4–9.5) | 8 (5–11.5) | U = 173.5; p = 0.494 |
| Neophagia II (Noyes/Y-maze) | |||
| Latency to contact (s) | 10.3 ± 1.2 | 9.2 ± 1.2 | t < 1; p > 0.20 |
| Latency to eat (s) | 109.1 ± 23.3 | 51.8 ± 11.0 | t(30) = 2.03; p = 0.051 |
| Latency to eat – latency to contact (s) | 61(14.5–139.8) | 21 (12.3–50.8) | U = 227.5; p = 0.184 |
Parametric data are presented as mean ± SEM and were analysed with t-tests. Non-parametric data are presented as median (inter-quartile range) and were analysed with Mann–Whitney U-tests. n = 14 WT; n = 11 GRM2/3−/− for test 1; n = 18 WT; n = 14 GRM2/3−/− for tests 2.