Table 2.

Correlation of miR-221 expression with clinical variables of patients with CMM.

Features	Overall survival			Disease-free survival
	HR	95% CI	P value	HR	95% CI	P value
Age	1.271	0.887–2.639	0.52	1.038	0.563–3.438	0.43
Sex	0.854	0.793–1.908	0.86	1.276	0.954–1.796	0.32
Thickness	2.189	0.976–6.095	0.06	3.097	2.178–5.887	0.03
Ulceration	1.965	0.657–4.992	0.12	2.886	0.875–7.354	0.09
Histologic type	0.782	0.378–7.891	0.44	0.835	0.278–4.009	0.31
Site	1.982	0.782–3.001	0.37	0.881	0.782–4.891	0.41
Metastasis	5.091	3.923–17.891	0.001	6.728	4.927–19.032	<0.001
Differentiation	3.082	1.909–7.811	0.009	2.901	1.927–7.032	0.011
Clinical stage	5.872	4.072–18.112	<0.001	5.891	3.991–19.903	<0.001
miR-221 expression	3.189	1.782–6.777	0.007	2.119	1.962–8.552	0.01

HR – hazard ratio; 95% CI – 95% confidence interval.