Table 1.
Ganglion cell classification
| Ganglion cell type | Nomenclature with stratification levels in the inner plexiform layer | Putative correlate to Völgyi et al. (2009) classification as determined by Helmstaedter et al. (2013) | Other potential matches or presence in transgenic lines |
|---|---|---|---|
| GC 1 | gc14–30 | G11 | A-type OFF sustained (Bleckert et al. 2014) |
| GC 2 | gc10–40 | — | — |
| GC 3 | gc15–42 | G7 | — |
| GC 4 | gc35–41 | G4 | — |
| GC 5 | gc37–46 | G4 | — |
| GC 6 | gc31–56 | G5 | — |
| GC 7 | gc36–51 | G8, 13 | W3a in TYW3 (Kim et al. 2010); local edge detector (Helmstaedter et al. 2013) |
| GC 8 | gc21–69 | G12 | — |
| GC 9 | gc30–63 | G17 | ON–OFF direction selective; DRD4-GFP (Huberman et al. 2009); BD, FSTL4-Cre-ER (Kim et al. 2010); W9 (Kay et al. 2011); Cdh6-CreER (Kay et al. 2011); TRHR-GFP (Rivlin-Etzion et al. 2011); Hb9-eGFP (Trenholm et al. 2011) |
| GC 10 | gc44–52 | G4, 5, 9 and/or 14 | W3b in TYW3 (Kim et al. 2010) |
| GC 11 | gc47–57 | G14 | — |
| GC 12 | gc76–86 | G1, 2 and/or 10 | A-type ON sustained, M4, M5 (Margolis & Detwiler, 2007; van Wyk et al. 2009; Estevez et al. 2012; Bleckert et al. 2014); inner α (Tagawa et al. 1999); ON Y-cell (Borghuis et al. 2013) |
| Melanopsin M1 | 0–20% | G19 | Opn4Cre/+; Z/EG (Ecker et al. 2010); Opn4-EGFP (Schmidt et al. 2008) |
| Melanopsin M2 | 80–100% | — | Opn4Cre/+; Z/EG (Ecker et al. 2010); Opn4-EGFP (Schmidt et al. 2008) |
| Melanopsin M3 | 0–20%, 80–100% | — | Opn4-EGFP (Schmidt et al. 2008) |
| JamB | 0–30% | G15 | JamB-Cre-ER (Kim et al. 2008) |
| W7a | 0–20%, 30–40% | — | TYW7 (Kim et al. 2010); A-type OFF sustained (Margolis & Detwiler, 2007; van Wyk et al. 2009; Bleckert et al. 2014); outer δ (Tagawa et al. 1999) |
| W7b | 30–40% | — | TYW7 (Kim et al. 2010); A-type OFF transient (Margolis & Detwiler, 2007; van Wyk et al. 2009); CB2-GFP (Huberman et al. 2008; but see Sümbül et al. 2014); outer α (Tagawa et al. 1999); OFF Y-cell (Borghuis et al. 2013); PV-5 (Münch et al. 2009) |
| ON DS (Hoxd10) | 55–70%, 15–20% | — | ON direction selective, Hoxd10-GFP (Dhande et al. 2013); SPIG1 (Yonehara et al. 2008) |
Classification of ganglion cell types (first column). Ganglion cell dendritic stratification levels in the inner plexiform layer where 0 indicates the outer border and 100 indicates the inner border (second column). Numbers that start with GC come directly from the nomenclature defined by Helmstaedter et al. (2013). Putative correlates with the Völgyi et al. (2009) classification of ganglion cells, as determined by Helmstaedter et al. (2013) (third column). Other potential matches or transgenic lines (fourth column). We note how speculative these correlations still are. Helmstaedter et al. (2013) assigned a level of correspondence to each of the Völgyi et al. (2009) types in their Supplemental Fig. 7.