Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Dec 8;207(5):599–613. doi: 10.1083/jcb.201405014

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Reuter et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 2. — BRCA2 displays heterogeneous mobility. (A) An image sequence showing diffusion of two BRCA2 particles, coming from an area above or below the observed focal plane, with transient binding. Individual frames are separated by 50 ms. (B) Tracked BRCA2 particle trajectories from the sequence in A are displayed as yellow lines superimposed on the 14th frame. (C) Other BRCA2 tracks representative of mobile or bound species. Bars, 0.5 µm. (D and F) The histograms show all particle jumps r from tracks classified as either bound (D) or mobile (F), respectively. (E and G) From these histograms, CDFs, normalized between 1 and 0 and displayed as decay, were derived and subjected to fitting with three components. The blue and red lines represent raw and fitted data, respectively. The data shown, obtained under nondamaged conditions, are representative of multiple experimental repeats (n > 10). Each dataset is based on at least 20 cells.

HHS Vulnerability Disclosure