Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Dec 8;207(5):615–626. doi: 10.1083/jcb.201404127

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Hamilton et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 2. — The genetics of chitinase secretion in S. marcescens. (A) A cartoon representing the organization of the S. marcescens Db10/11 chromosome around region 3,031,956–3,036,024 bp. The red arrows indicate the positions of three transposon insertion sites found to disrupt ChiC secretion. One was located 129 bp upstream of chiR (SMDB11_2876), one was 23 bp upstream of chiW (SMDB11_2874), and one was at position 165 within chiW. (B) Cartoon depicting the predicted subcellular localizations and topologies of the chiWXYZ gene products. ChiW is a member of the phage holin-3 family and is predicted to span the membrane three times with an N terminus–out, C terminus–in topology. The predicted endopeptidase ChiX does not have a classical signal peptide and is hypothesized to reach the periplasm via the ChiW holin. The ChiY protein is synthesized with a classical N-terminal type II signal peptide, which is typical of outer membrane lipoproteins. The ChiZ protein is predicted to have a single N-terminal transmembrane domain and span the membrane with an N terminus–in, C terminus–out topology. N, N terminus; C, C terminus.