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. Author manuscript; available in PMC: 2015 Nov 15.
Published in final edited form as: Eur J Pharmacol. 2014 Sep 16;743:98–105. doi: 10.1016/j.ejphar.2014.09.006

Fig. 3. Comparison of ICSS after treatment with vehicle + vehicle and either RTI-118 + cocaine (A) or U69,593 + cocaine (B).

Fig. 3

Abscissae: frequency of electrical brain stimulation in log Hz. Ordinates: percent maximum control reinforcement rate (%MCR). Treatments are indicated in legends, and drug doses are presented in units of mg/kg. Filled points represent frequencies at which ICSS rates after drug treatments were different from vehicle treatment as determined by two-way ANOVA followed by Holm-Sidak post hoc test, P<0.05. All data show mean ± S.E.M. for five (RTI-118 + cocaine) or six (U69,593 + cocaine) rats.