Table 7.
Comparison of the genotype and allele frequencies of XRCC1 Arg399Gln (G>A) polymorphism with HapMap populations.
| POPULATION | N | GENOTYPE FREQUENCY (%) | ALLELE FREQUENCY (%) | P VALUE | |||
|---|---|---|---|---|---|---|---|
| GG | GA | AA | G | A | |||
| Present study (SI) | 128 | 46.9 | 38.3 | 14.8 | 66.0 | 34.0 | Ref. |
| CEU | 224 | 38.4 | 50.0 | 11.6 | 63.4 | 36.6 | 0.4846 |
| HCB | 84 | 52.4 | 40.5 | 7.1 | 72.6 | 27.4 | 0.1518 |
| JPT | 172 | 52.3 | 40.7 | 7.0 | 72.7 | 27.3 | 0.0788 |
| YRI | 226 | 77.9 | 22.1 | 0 | 88.9 | 11.1 | <0.0001 |
| GIH | 176 | 34.1 | 50.0 | 15.9 | 59.1 | 40.9 | 0.0824 |
| MEX | 98 | 42.9 | 49.0 | 8.2 | 67.3 | 32.7 | 0.7662 |
Abbreviations: N, number of subjects; SI, South Indian; CEU, Utah residents with Northern and Western European ancestry; HCB, Han Chinese in Beijing, China; JPT, Japanese in Tokyo, Japan; YRI, Yoruba in Ibadan, Nigeria; GIH, Gujarat Indians in Houston, TX; and MEX, Mexican ancestry in Los Angeles, CA.