. Author manuscript; available in PMC: 2014 Dec 9.

Published in final edited form as: J Nucl Med. 2014 Oct 30;55(12):2032–2037. doi: 10.2967/jnumed.114.145102

Table 1. Pertinent Characteristics of ⁸⁹Zr-αGPC3 and ⁸⁹Zr-αGPC3-F(ab′)2.

Probe	Molecular weight^* (kDa)	K_d^* (nM)	Blood half-life (h)	Tumor-to-liver ratio at 4 h	Tumor-to-liver ratio at 72 h
⁸⁹Zr-αGPC3	~155	0.03	115	1.2	30.5
⁸⁹Zr-αGPC3-F(ab′)2	~110	0.03	11	23.2	15.1

Measurements were performed on whole mAb and F(ab′)2 prior to conjugation with isothiocyanotobenzyldesferrioxamine.

Table 1. Pertinent Characteristics of 89Zr-αGPC3 and 89Zr-αGPC3-F(ab′)2.