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. Author manuscript; available in PMC: 2014 Dec 9.
Published in final edited form as: Curr Protein Pept Sci. 2007 Jun;8(3):293–310. doi: 10.2174/138920307780831857

Figure 5. Amino acid sequence alignment of PYRIN domains.

Figure 5

Clustal W alignment of PYRIN domains, including viral POPs, murine HIN-200 family members p202, p203, p204, and D3, as well as zebrafish caspases. The α-helices, as defined for ASC, are marked on top (H1-6) [205]. Conserved residues are highlighted. Mainly residues of the hydrophobic core are conserved, but the linker distance is variable.