Table 3.

Participant preferences, concerns, and illustrative quotes regarding Automation and Integration theme.

Preference		Concern	Quote
Alarms and reminders for treatments
	Reminders for new, unusual, cyclical prescriptions	Don’t need alarms for common or routine treatments	A: “Last week they had me on a medication that I am not normally on, and I had to take that twice a day, so something [to remind me] might be helpful because…[for the medications I am normally on] I pretty much know the drill I’ve been taking them my whole life, but for stuff like that where it’s not part of my normal routine that could be helpful.” [Age 23, Male]
	Motivating or persistent alarms	Alarms can feel like nagging, are easy to “snooze” or ignore	B: “It needs to find the right line between annoying and not annoying…it needs to be just the perfect amount of annoying that I’ll actually do it.” [Age 24, Female]
	Well-timed reminders	Alarms that sound at inconvenient times	C: “The problem with alarm apps is that they tell you once and then you can…snooze…or just end it, and…if there’s a problem with taking the medication right then, that’s not good. For instance, if you’re driving you snooze and 5 minutes later it goes off again and you’re still driving…it would be really good if it could…[remind you later when] you’re not moving anymore.” [Age 30, Male]
Pharmacy refills
	Automatic, triggered by available medication data (eg, new or previous fills, adherence data)	Refill barriers: forgetting, late requests, time-consuming calls, pre-authorizations	D: “The biggest thing for me would be the ability to manage medications…all in one place …If I need to refill prescriptions, … being able to potentially do it straight from my phone … with the ability to tie into … wherever I get my medicine from so that when I do need to renew it or refill it, it's … the click of a button or scanning of a bar code in the phone…If I could have one central location that had all of my prescriptions that dealt with cystic fibrosis in one spot and I could refill them from that spot, that would make life a lot easier.” [Age 31, Male]
			E: “A lot of people need reminders when they need to refill their prescription so…keeping track of how many [doses of medication] do I have left?…Keep track of when I filled that and automatically populate 30 ampules…then it counts down every time you use, being able to track when you’re supposed to order your medication again.” [Age 27, Male]