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. 2014 Oct 29;3(4):e49. doi: 10.2196/resprot.3337

Table 4.

Modifications to communication protocol resulting from stakeholder (patients and genetic counselors) surveys (n=86) and session tape reviews (n=33).a

Modifications to the communication protocol Reason for tape review Reviewer observations Patient comments GCbcomments
1. Clarified telephone disclosure (TD) instructions in pre-test counseling

-Visual aid: read in advance and have for session -Visual aid: read in advance and have for session



-Schedule sufficient time for session and processing -Schedule sufficient time for session and processing



-Have support person -Have support person
2. Scheduled TD appointments -Increase in anxiety or depression or decline in knowledge Session occurred in non-private environment without visual aids -Session was disrupted (eg, workplace, childcare) -Session was disrupted (eg, workplace, childcare)



-Session disrupted other activities -Difficult to reach patient (“phone tag”)
3. Refined visual aids

Visual aids confusing Visual aids confusing
4. Improved disclosure checklist: -Increase in anxiety -Some elements of disclosure checklist omitted
Who else is on call/present?
-Enhanced formatting



-Included information on GINAc
-Patient concerned about genetic discrimination

5a. GC training: -Increase in anxiety or depression -High baseline anxiety -Communication challenging without visual cues Interpreting patient affective response and providing emotional support challenging without visual cues
-Recognizing signs of negative affect in the absence of visual cues -Patient/GC discordance -Inaccurate expectations

-Effective use of affective and situational probes



-Need to pace session to meet patient needs



-Identifying risk factors for negative affective response -Positive test result -Personal history of cancer -Need to be prepared for all results


-Treatment decision pending



-Family history (uninformative or extensive cancer)



-Need for additional tests (self or family members)

5b. GC training: -Decline in knowledge Low health literacy
Interpreting patient cognitive response and providing remediation challenging without visual cues
-Identifying risk factors for confusion



-Recognizing signs of confusion



-Techniques to improve patient comprehension -VUSdtest result


-Effective use of knowledge and situational probes and “teach back” to assess understanding



5c. GC training: -Decline in knowledge

-Responding to challenging patients/situations
-Effective use of situational probes to control situation


-Controlling the session
6. Conduct larger trial to evaluate outcomes for potentially vulnerable subgroups -Positive test result -Need for additional testing (self or family members) TD might be more challenging in some situations (eg, Positive test result, need for additional testing, poor understanding after pre-test counseling, psychological factors) TD might be more challenging in some situations (eg, Psychosocial comorbidities, English as a second language, pending treatment decisions, personal cancer history)

-VUS test result -Personal history of cancer



-Family history of cancer


-Increase in anxiety or depression -Uninformative negative result



-Insurance issues

aBased on a priori review criteria

bGC: genetic counselor

cGINA: Genetic Information Nondiscrimination Act

dVUS: variant of uncertain significance