Table 3.
Radiobiological indices of the pmiR-210 and Ctrl cells
| D0 | Dq | N | SF2 | |
| PmiR-210 | 1.73% ± 0.01% | 1.56% ± 0.02%a | 1.97% ± 0.03%a | 43.62% ± 0.14%a |
| Ctrl | 1.75% ± 0.02% | 1.89% ± 0.13% | 3.13% ± 0.07% | 67.83% ± 0.16% |
a
P < 0.05, vs Ctrl. PmiR-210: TE-1R cells transfected with the miR-210 mimic; Ctrl: TE-1R cells transfected with a nonsense sequence. The experiments were performed in triplicate. D0: Mean lethal dose; Dq: Quasi-threshold dose; N: Extrapolated number; SF2: Survival fraction after 2-Gy irradiation. The lower Dq and N of the pmiR-210 cells compared with those of the Ctrl cells indicate a less efficient repair of radiation damage. A low SF2 value indicates a level of high sensitivity to radiotherapy.