Table 3.
Multivariate factor effects by type of death
| Factor1 | β (SE)2 | 95%CI2 | P-value3 |
| Breast cancer survival4 | |||
| Treatment (Tamoxifen, Tamoxifen + Octreotide LAR) | 0.0008(0.17) | [-0.33, 0.33] | 1.00 |
| Adjuvant chemotherapy (no, yes) | 0.2553 (0.20) | [-0.14, 0.65] | 0.20 |
| Number of positive nodes | |||
| (0, Nx, 1-3, ≥ 4+) | -0.2524 (0.08) | [-0.41,-0.10] | 0.002 |
| Hormone receptor status (ER-PR-, unknown ER/PR, ER+ and/or PR+) | 0.2821 (0.13) | [0.03,0.54] | 0.03 |
| Tumour size (T1, ≥ T2, unknown) | -0.6521 (0.18) | [-1.00,-0.30] | 0.0003 |
| Other Cause Survival | |||
| Treatment (Tamoxifen, Tamoxifen + Octreotide LAR) | 0.1236 (0.18) | [-0.23, 0.48] | 0.49 |
| Adjuvant Chemotherapy (no, yes) | -0.0703 (0.23) | [-0.52, 0.38] | 0.76 |
| Number of positive nodes | |||
| (0, Nx, 1-3, ≥ 4+) | -0.0723 (0.08) | [-0.23, 0.08] | 0.38 |
| Hormone receptor status (ER-PR-, unknown ER/PR, ER+ and/or PR+) | -0.3852 (0.26) | [-0.89,0.12] | 0.13 |
| Age (years) | -0.0389 (0.01) | [-0.06,-0.02] | 0.002 |
| BMI (continuous) | -0.0395 (0.01) | [-0.06,-0.02] | 0.01 |
1
Cause-specific survival model was built using ln(survival time) having linear function of β x (factor values). The model had forced inclusion of treatment and stratification factors (adjuvant chemotherapy, nodal status, and hormone receptor status) with step-wise forward inclusion of other baseline factors;
2
β is effect of factor; SE is standard error; CI is confidence interval assuming β is approximately normally distributed;
3
P-value is that for a Wald statistic;
4
Higher values of continuous C-peptide were associated with worse BrCa (P = 0.08).