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. 2014 Dec 10;5(5):845–857. doi: 10.5306/wjco.v5.i5.845

Table 2.

Evidence supporting recommended dose-fractionation schedules

Indication Recommended schedule Selected references Level of evidence
Uncomplicated bone metastases (spine, non-spine) [15] 1
8Gy/1 [10,32,39,41,60,61] 5
Neuropathic pain 8Gy/1 or 20Gy/5 [38] 1
Impending SCC, RT alone Multifraction [41] 5
[36] 4
Impending pathologic fracture, RT alone 20-40Gy/5-20 [45] 1

RT: Radiotherapy; SCC: Spinal cord compression.