Table 4.
Grey shading indicates dose-fractionation schedules which would be supported by current evidence
| Case | N treating with EBRT | 8Gy/1 | 20Gy/5 | 30Gy/10 | Other | Median (Range) |
| Uncomplicated-non-spine | ||||||
| Nakamura case 1 (Japan, 2012) | 51 | 13.70% | 9.80% | 66.70% | 9.80% | NR (NR) |
| Uncomplicated-spine | ||||||
| Hartsell case 2 (United States, 1998) | 229 | 4% recommended < 30Gy | 76% recommended 30-35Gy 20% recommended > 35Gy | NR (15Gy/5 – 47.5Gy/25) | ||
| Nakamura case 2 (Japan 2012) | 51 | 5.90% | 3.90% | 78.40% | 11.80% | NR (NR) |
| Chow case 3 (Canada, 2000) | 171 | 15.80% | 66.10% | 8.80% | 9.4%3 | NR (8Gy/1 – 30Gy/10) |
| Chow case 2 (Canada, 2000) | 170 | 15.90% | 64.70% | 8.20% | 11.2%3 | NR (8Gy/1 – 30Gy/10) |
| Fairchild case 3 (Intl, 2009) | 867 | 18.3%2 | 19.8%2 | 41.9%2 | 20.00% | 30Gy/10 (3Gy/1 - 55Gy/22) |
| De Bari case 2 (Italy, 2011) | 107€ | 22.20% | 50.10% | 26.80% | 0.90% | NR (NR) |
| Roos case 3 (Aust/NZ, 2000) | 531€ | 39.6%€ | 35.8%€ | 15.1%€ | 9.4%€ | NR (8Gy/1 - 40Gy/18) |
| Complicated-neuropathic pain | ||||||
| Nakamura case 3 (Japan, 2012) | 52 | 0% | 5.80% | 78.80% | 15.40% | NR (NR) |
| Fairchild case 4 (Intl, 2009) | 844 | 6.6%2 | 29.0%2 | 42.8%2 | 21.60% | 30Gy/10 (3Gy/1 – 45Gy/18) |
| Roos case 4 (Aust/NZ, 2000) | 531€ | 13.2%€ | 52.8%€ | 24.5%€ | 9.4%€ | NR (8Gy/1 - 40Gy/20) |
| Complicated-impending spinal cord compression and impending pathologic fracture | ||||||
| De Bari case 4 (Italy, 2011) | 113€ | 30.60% | 25.80% | 28.20% | 15.4%3 | NR (NR) |
1
41 specialists/12 trainees;
2
Takes into account multiple dose fractionation schemes listed per respondent;
3
Includes unknown/missing responses; €: Extrapolated from data reported or from figure. EBRT: External beam radiotherapy; Intl: International; NR: Not reported.