Figure 2.

Clinical Features of Individual 2

(A–C) Clinical photographs of individual 2 performed at the age of 5 months showing micrognathia, upslanting palpebral fissures, short nose with anteverted nares, thin eyebrows, and cleft palate.

(D and F) Clinical photographs of both hands of individual 2 showing the clinodactyly of the index fingers, which is more pronounced on the left side.

(E and G) Hand radiographs of individual 2 performed at the age of 3 months showing a triangular-shaped bone inserted between the second metacarpal and its proximal phalanx bilaterally causing radial deviation of the index finger. On the left hand an additional pin-shaped ossification center is visible.