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. 2014 Nov 26;3(11):e149. doi: 10.1038/psp.2014.47

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Copyright © 2014 American Society for Clinical Pharmacology and Therapeutics

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Schematic of Quantitative Systems Pharmacology model for evaluation of LDLc lowering with anti-PCSK9 as monotherapy and combination with statins. Ch., cholesterol; Circ., circulating; LDLc, low density lipoprotein cholesterol.