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OS (from the start of the run-in period) for patients who did not develop grade ⩾2 rash during the 4-week run-in period who were randomised to receive standard therapy (gemcitabine plus erlotinib 100 mg per day) or dose escalation (gemcitabine plus escalating doses of erlotinib), compared with non-randomised patients who developed grade ⩾2 rash during the run-in period. Abbreviation: OS=overall survival.
