Table 3. Cox regression multivariate analysis of variables affecting survival.
|
|
95% Confidence interval |
|
|
---|---|---|---|---|
Variables | Hazard ratio | Lower | Upper | Significance (P-value) |
Age (per year) |
1.01 |
0.95 |
1.08 |
0.730 |
Sex | ||||
Female | 1.00 | |||
Male |
0.95 |
0.63 |
1.43 |
0.806 |
Diagnostic category | ||||
Interval | 1.00 | |||
Screen-detected |
0.45 |
0.29 |
0.69 |
<0.001 |
Index of multiple deprivation quintile category | ||||
Most affluent | 1.00 | |||
2 | 0.75 | 0.29 | 1.92 | 0.549 |
3 | 1.02 | 0.44 | 2.34 | 0.962 |
4 | 1.78 | 0.79 | 4.02 | 0.168 |
Most deprived |
2.01 |
0.92 |
4.40 |
0.079 |
ASA grade | ||||
ASA 1–2 | 1.00 | |||
ASA 3–5 |
1.56 |
0.90 |
2.72 |
0.114 |
Tumour site | ||||
Distal to splenic flexure | 1.00 | |||
Splenic flexure and proximal |
1.84 |
1.19 |
2.83 |
0.006 |
Dukes' stage | ||||
Dukes' A | 1.00 | |||
Dukes' B | 3.85 | 1.41 | 10.54 | 0.009 |
Dukes' C | 6.51 | 2.49 | 16.97 | <0.001 |
Dukes' D | 35.30 | 13.57 | 91.87 | <0.001 |
Abbreviation: ASA=American Society of Anaesthesiologists.