Table 1. The relationship between ENST00000480739 expression and clinicopathologic parameters in PDAC (35 pairs).
| |
LncRNA expression |
|
|
|
|---|---|---|---|---|
| Clinicopathologic parameters | High | Low | Number of cases | P-value |
|
Age (years) | ||||
| ⩽60 | 9 | 6 | 15 | 0.2302 |
| >60 |
11 |
9 |
20 |
|
|
Gender | ||||
| Male | 7 | 8 | 15 | 0.4043 |
| Female |
12 |
8 |
20 |
|
|
Diameter (cm) | ||||
| ⩽4 | 14 | 8 | 22 | 0.5641 |
| >4 |
6 |
7 |
13 |
|
|
Degree of differentiation | ||||
| Well and moderately | 10 | 9 | 19 | 0.3778 |
| Poorly |
7 |
9 |
16 |
|
|
TNM stage | ||||
| I | 10 | 3 | 13 | 0.0354a |
| II |
6 |
16 |
22 |
|
|
Neural invasion | ||||
| Yes | 9 | 10 | 19 | 0.4317 |
| No |
8 |
8 |
16 |
|
|
Lymph node metastasis | ||||
| Yes | 5 | 13 | 18 | 0.0004a |
| No | 12 | 5 | 17 | |
Abbreviations: lncRNAs=long non-coding RNA; PDAC=pancreatic ductal adenocarcinoma; TNM=tumour node metastasis.
Patients were staged in accordance with the 7th Edition of the AJCC Cancer's' TNM Classification. According to the interpretation of NCCN guidelines for surgical treatment of pancreatic carcinoma, PDAC with stage III and stage IV are unresectable.
a
Statistically significant (P<0.05).