Table 1.

Correlation between HH pathway factors and pathological parameters in glioma patients

Feature	Shh on ECs				Gli1 on pGCs
	Negative (n)	Moderate (n)	High (n)	p	Negative (n)	Moderate (n)	High (n)	p
WHO grade
II	9	18	6	0.041*	13	12	8	0.022*
III	4	5	7		2	5	9
IV	2	7	7	0.112**	3	7	6	0.068**
Gender
Male	10	21	16	0.231	5	7	6	0.635
Female	5	9	4		13	17	17
Age
≥ 60 years	0	2	3	0.095	0	2	3	0.152
< 60 years	15	28	17		18	22	20
KPS
≥ 80	13	21	13	0.363	11	16	17	0.839
< 80	7	9	5		7	8	6
Tumour location
Frontal	13	15	8	0.971	8	16	9	0.671
Non-frontal	7	15	10		10	8	14

^*Unpaired Student's t-test was used for comparison between low-grade (grade II) and high-grade (grade III and IV) gliomas.

^**Kruskal–Wallis analysis was used for comparison of Shh on ECs and Gli1 on pGCs in the three grades of glioma.

KPS, Karnofsky Performance Scale.