Table 2.

The Influence of Maternal Demographics, Exposures, and Medical History on Neonatal TSH

	Mean TSH (mIU/L)±SD	r2	1 P-value	r2	2 P-value
Maternal age N=681		0.005	0.36	0.060	0.49
<18 years (N=16)	5.0±3.9
18–25 years (N=272)	5.7±3.8
26–35 years (N=315)	5.8±3.7
>35 years (N=78)	6.0±3.1
Maternal pre-pregnancy BMI N=262		0.003	0.72	0.079	0.50
<=25 (N=143)	5.9±3.3
25-<30 (N=48)	6.2±3.7
>=30 (N=71)	6.5±4.2
Smoking during pregnancy N=599		0.007	0.04	0.067	0.05
No (N=448)	5.8±3.6
Yes (N=151)	5.3±3.9
Alcohol use during pregnancy N=577		<0.001	0.52	0.061	0.48
No (N=532)	5.7±3.6
Yes (N=45)	5.8±3.2
Drug use during pregnancy N=564		0.007	0.04	0.070	0.05
No (N=539)	5.7±3.6
Yes (N=25)	4.5±3.7
Caffeine use during pregnancy N=245		0.003	0.39	0.094	0.57
No (N=89)	6.0±3.2
Yes (N=156)	5.8±3.7
Vitamin use during pregnancy N=283		<0.001	0.85	0.062	0.64
No (N=8)	6.0±3.5
Yes (N=275	5.8±3.5
Vitamin use 3 months prior to pregnancy N=162		<0.001	0.83	0.138	0.71
No (N=60)	6.0±3.9
Yes (N=102)	5.9±3.3
Parity N=629		0.015	2x10−3	0.072	8x10−4
Nulliparous (N=347)	6.1±3.9
Multiparous (N=282)	5.2±3.3
Prenatal Steroids N=647		0.018	6x10−4	0.057	0.24
No (N=178)	6.5±4.1
Yes (N=469)	5.4±3.5
Antibiotics during pregnancy or delivery N=231		0.003	0.43	0.064	0.44
No (N=32)	6.3±3.7
Yes (N=199)	5.8±3.7
Maternal thyroid disease N=277		<0.001	0.66	0.101	0.51
No (N=256)	5.7±3.4
Yes (N=21)	6.0±3.5
Maternal urinary tract infection N=450		0.002	0.42	0.057	0.32
No (N=362)	5.7±3.5
Yes (N=88)	6.1±4.2
Sexually transmitted disease when pregnant N=238		0.012	0.09	0.075	0.16
No (N=216)	5.7±3.6
Yes (N=22)	4.3±2.5

¹P-value: single variable one-way ANOVA.

²P-value: ANOVA adjusted for gestational age.