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. Author manuscript; available in PMC: 2014 Dec 9.
Published in final edited form as: Pharm Res. 2009 Jun 16;26(8):1986–1994. doi: 10.1007/s11095-009-9914-2

Figure 2.

Figure 2

Kinetics of total octreotide remaining (A), native octreotide content (B) and divalent cation remaining (C) after incubation of PLGA microspheres in PBST at 37°C. ■ Formulation 1, no additive was added to organic phase; ▲Formulation 2, adding 25 mg NaCl to organic phase; ▼Formulation 3, adding 25 mg CaCl2 to organic phase; and ✩Formulation 4, adding 25 mg MnCl2 to organic phase