Figure 1.

Current voltage-relationship of K⁺ -current recorded in SH-SY5Y neuronal cell line. (A) A sigmoid I/V relationship of the mean K⁺ ions currents (n = 46) recorded in the control condition (CTRL) in asymmetrical K⁺ ions concentrations (int K⁺: 132 × 10⁻³ M; ext K⁺: 2.8 × 10⁻³ M), in the presence of internal 1.6 × 10⁻⁶ M concentration of free Ca²⁺ ions, in the range of potentials going from −150 to +110 mV, HP = −60 mV (Vm), using whole-cell patch-clamp technique. The K⁺-current was leak subtracted and normalized to capacitance. The intercept of the I/V curve on the voltage membrane axis was −33 mV. (B) Sample traces of the K⁺ ions current recorded in the control conditions. (C) Sample trace of the leak current recorded in asymmetrical K⁺ ion concentrations in the presence of Ba²⁺ ions (5 × 10⁻³ M) and TEA (5 × 10⁻³ M) in the bath solutions.