Table 1.
Affibody molecule | Affinity for hFcRn, nM | Affinity for mFcRn, nM | Melting temperature, °C | ||
pH 6.0 | pH 7.4 | pH 6.0 | pH 7.4 | ||
ZFcRn_4 | 50 | >1,000 | 350 | >5,000 | 58 |
ZFcRn_16 | 14 | >500 | 95 | >500 | 59 |
ZFcRn_2 | 12 | >500 | 90 | >500 | 49 |
Affibody molecule | Affinity for hFcRn, nM | Affinity for mFcRn, nM | Melting temperature, °C | ||
pH 6.0 | pH 7.4 | pH 6.0 | pH 7.4 | ||
ZFcRn_4 | 50 | >1,000 | 350 | >5,000 | 58 |
ZFcRn_16 | 14 | >500 | 95 | >500 | 59 |
ZFcRn_2 | 12 | >500 | 90 | >500 | 49 |