Table 5.
Reason for non-completion | No (%) |
---|---|
Insufficient/poor patient recruitment | 36 (44) |
Lack of funding to continue trial | 8 (10) |
Trial terminated early owing to negative results/futility | 8 (10) |
Withdrawal of trial management or clinical investigators | 7 (9) |
Trial administration or conduct problems | 4 (5) |
Trial lost clinical relevance | 4 (5) |
Trial product/device/drug withdrawn from market | 3 (4) |
Trial termination based on safety or toxicity data | 2 (2) |
Trial terminated early owing to positive results | 1 (1) |
Missing | 8 (10) |
14/81 did not disclose reason for termination on ClinicalTrials.gov; emails were identified and sent to 10/14 authors, with no contact available for remaining 4/14.