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. Author manuscript; available in PMC: 2014 Dec 9.
Published in final edited form as: Biochem Biophys Res Commun. 2014 Apr 13;447(2):352–357. doi: 10.1016/j.bbrc.2014.04.006

Figure 1. Osteoblastic cell model for mechanical stimulation.

Figure 1

(A) Primary osteoblasts derived from the calvaria of αv flox/flox mice were infected with adeno-LacZ (LacZ) or adeno-Cre (Cre) vectors and, and RNA and protein were extracted for Itgav mRNA and protein expression. ***p<0.001 (B) Calvaria-derived primary osteoblasts respond to fluid shear stress (FSS) with increased expression of Egr1 and Fos. RNA was isolated at 0 and 30 min following FSS, and gene expression was analyzed by qRT-PCR. **p<0.01, *p<0.05 (n=4 each group).