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. 2014 Dec 2;9:5575–5590. doi: 10.2147/IJN.S72819

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© 2014 Qin et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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(A) UV-vis spectra of the HRBC suspensions treated with [(Au⁰)₃₀₀-G5.NHAc-FI-mPEG] DENPs at different Au concentrations (100 μM [3], 200 μM [4], 300 μM [5], and 400 μM [6], respectively) and (B) hemolysis percentage of the Au DENPs as a function of the Au concentration.

Notes: In both (A) and (B), H₂O (1) and PBS (2) were used as positive and negative control, respectively. Inset of (A) shows the enlarged UV-vis spectra of samples 2–6.

Abbreviations: DENP, dendrimer-entrapped gold nanoparticle; FI, fluorescein isothiocyanate; HRBC, human red blood cell; OD, optical density; PBS, phosphate-buffered solution; PEG, polyethylene glycol; UV-vis, ultraviolet–visible.