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. 2014 Dec 2;9:5575–5590. doi: 10.2147/IJN.S72819

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© 2014 Qin et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Representative micro-CT images of macrophages in atherosclerosis of ApoE-KO mice before and after intravenous injection with [(Au⁰)₃₀₀-G5.NHAc-FI-mPEG] DENPs for 20 minutes and 2, 4, and 6 hours.

Notes: (A) coronal plane, (B) sagittal plane, (C, D) transversal planes, and the corresponding 3D renderings of in vivo CT images (E, F). The yellow, white, and the red arrows point to the inferior vena cava vein, the renal vein, and the pulmonary vein of the mouse, respectively.

Abbreviations: ApoE-KO, apolipoprotein E knockout; CT, computed tomography; DENP, dendrimer-entrapped gold nanoparticle; FI, fluorescein isothiocyanate; PEG, polyethylene glycol.