Table 1.
DNA polymerase family X members used for sequence alignments and subsequent phylogenetic analyses.
| Prokaryotic DNA polymerase family X sequences | |
| 1. | Aeromonas hydrophila subsp. hydrophila ATCC 7966 (gb|ABK36337.1|) |
| 2. | Aquifex aeolicus VF5 (ref|NP 213981.1|) |
| 3. | Aurelia sp. 1 sensu (UniProtKB: F7J5W8 (F7J5W8 9CNID)) |
| 4. | Bacillus amyloliquefaciens (UniProtKB: F4EI46 (F4EI46 BACAM)) |
| 5. | Bacillus pumilus SAFR-032 (gb|ABV63179.1|) |
| 6. | Bacillus subtilis subsp. subtilis str. 168 (emb|CAB14819.1|) |
| 7. | Deinococcus radiodurans R1 (ref|NP 294190.1|) |
| 8. | Desulfotomaculum reducens MI-1 (ref|YP 001112987.1|) |
| 9. | Listeria monocytogenes serotype 4b str. F2365 (ref|YP 013839.1|) |
| 10. | Methanosarcina mazei Go1 (ref|NP 633918.1) |
| 11. | Mycobacterium tuberculosis (ref|NP 218373.1) |
| 12. | Salpingoeca rosetta sp. ATCC 50818 (gb|EGD82858.1|) |
| 13. | Sphingobacterium spiritivorum ATCC 33300 (ref|ZP 03968066.1|) |
| 14. | Staphylococcus aureus subsp. aureus JH9 (ref|YP 001246578.1|) |
| 15. | Staphylococcus pseudintermedius str. HKU10-03 (UniProtKB: E8SFK2 STAPH) |
| 16. | Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 (ref|YP 301742.1|) |
| 17. | Thermoplasma volcanium GSS1 (ref|NP 111375.1|) |
| 18. | Thermus aquaticus (tr|P77987|P77987 THEAQ) |
| 19. | Thermus thermophilus HB8 (ref|YP 144416.1|) |
| 20. | Thiobacillus denitrificans ATCC 25259 (gb|AAZ97399.1|) |
| 21. | Vibrio anguillarum 775 (gb|AEH34679.1|) |
| Eukaryotic DNA polymerase family X sequences | |
| 1. | Acromyrmex echinatior (ant; gb|EGI68014.1|) |
| 2. | Ailuropoda melanoleuca (giant panda; ref|XP 002918406.1|) |
| 3. | Ailurus fulgens (red panda; gb|ADT64454.1|) |
| 4. | Anolis carolinensis (lizard; ref|XP 003228273.1|) |
| 5. | Arabidopsis thaliana (mouse ear cress flowering plant; λ-NCBI GenPept: ADM33939.1 gi:304440990) |
| 6. | Ashbya gossypii (filamentous fungus; UniProtKB: Q757Q1 ASHGO) |
| 7. | Bos taurus (cow; β-ref|NP 001029936.1|, λ-ref|NP 001179488.1|, μ-gb|AAX46342.1|, Tdt-UniProtKB: P06526 TDT BOVIN) |
| 8. | Callithrix jacchus (marmoset; β-ref|XP 002757050.1|) |
| 9. | Candida glabrata (haploid yeast; UniProtKB: Q6FKY2 CANGA) |
| 10. | Canis lupus familiaris (domestic dog; β-NCBI GenPept: AAV66968, λ-ref|XP 861980.1|, Tdt-ref|XP 005637632.1|, μ-RefSeq status WITHDRAWN) |
| 11. | Cricetulus griseus (guinea pig; gb|EGV95023.1|) |
| 12. | Crithidia fasciculate (parasitic protist; gb|AAA68599.2|) |
| 13. | Cryptococcus neoformans var. neoformans B-3501A (encapsulated yeast; ref|XP 777918.1|) |
| 14. | Cryptococcus neoformans var. neoformans JEC21 (encapsulated yeast; ref|XP 568043.1|) |
| 15. | Cryptococcus neoformans var. grubii H99 (fungal pathogen causing fatal meningitis; λ-ref|XP 773693.1|) |
| 16. | Danio rerio (zebrafish; β-ref|NP 001003879|, λ-ref|NP 998408.1|, Tdt-gb|AAI63775.1|) |
| 17. | Dictyostelium discoideum (slime mold; UniProtKB: Q1ZXF2 DICDI) |
| 18. | Equus caballus (horse; β-ref|XP 001489108.2|) |
| 19. | Fusarium graminearum PH-1 (fungal plant pathogen; ref|XP 382072.1|) |
| 20. | Gallus gallus domesticus (chicken; β-ref|XP 001143904|, λ-ref|XP 001232209.2|, Tdt-UniProtKB: P36195 TDT CHICK) |
| 21. | Homo sapiens (human; β-ref|NP 002681.1|, λ-UniProtKB: Q9UGP5 DPOLL HUMAN, μ-UniProtKB: Q9NP87 DPOLM HUMAN, Tdt-UniProtKB: P04053 TDT HUMAN) |
| 22. | Kluyveromyces lactis (yeast; UniProtKB: Q6CX59 KLULA) |
| 23. | Leishmania infantum (parasite; gb|AAF00495.1|) |
| 24. | Leishmania major (parasite; UniProtKB: Q4QI80 LEIMA) |
| 25. | Lepeophtheirus salmonis (sea louse; tr|C1BUF7|C1BUF7 9MAXI) |
| 26. | Loxodonta africana (elephant; ref|XP 003412553.1|) |
| 27. | Macaca mulatta (rhesus monkey; β-ref|XP 001097548.1|, λ-ref|NP 001253835.1|) |
| 28. | Monodelphis domestica (gray short-tailed opossum; β-ref|XP 001373104.1|, λ-ref|XP 001369819.1|, μ-UniProtKB: F6SV89 MONDO, Tdt-UniProtKB:O02789 TDT MONDO) |
| 29. | Mus musculus (mouse; β-ref|NP 035260.1|, λ-UniProtKB: Q9QXE2 DPOLL MOUSE, μ-UniProtKB: Q9JIW4 DPOLM MOUSE, Tdt-UniProtKB: P09838 TDT MOUSE) |
| 30. | Nematostella vectensis (starlet sea anemone; β-ref|XP 001618045.1|) |
| 31. | Neurospora crassa OR74A (bread mold; β-ref|XP 961407.1|, λ-ref|XP 963912.2|) |
| 32. | Ornithorhynchus anatinus (platypus; ref|XP 001509890.2|) |
| 33. | Oryctolagus cuniculus (rabbit; ref|XP 002720811.1|) |
| 34. | Pan troglodytes (chimpanzee; β-ref|XP 001143904|, λ-ref|NP 001267179.1|, Tdt-ref|XP 521569.1|) |
| 35. | Platichthys flesus (European flounder; emb|CAC28866.1|) |
| 36. | Pongo abelii (orangutan; ref|XP 002819090.1|) |
| 37. | Rattus norvegicus (rat; β-ref|NP 058837.2|, λ-UniProtKB: Q5RKI3 DPOLL RAT, μ-ref|NP 001011912.1|, Tdt-gb|EDL94195.1|) |
| 38. | Saccharomyces cerevisiae (budding yeast; UniProtKB: P25615 DPO4 YEAST) |
| 39. | Schizosaccharomyces pombe 972h (fission yeast; ref|NP 592977.1|) |
| 40. | Strongylocentrotus purpuratus (purple sea urchin; ref|XP 787665.2|) |
| 41. | Taeniopygia guttata (zebra finch; ref|XP 002186553.1|) |
| 42. | Takifugu rubripes (Fugu rubripes puffer fish; β-ref|XP 003974975.1|, λ ref|XP 003972614.1|, μ-ref|XP 003965471.1|, Tdt-ref|NP 001027915.1|) |
| 43. | Tetraodon nigrovirdis (green spotted puffer fish; β-ref|XP 003974975.1|, λ-emb|CAG03351.1|, μ-emb|CAG05362.1|, Tdt-emb|CAG10152.1|) |
| 44. | Tribolium castaneum (red flour beetle; dbj|BAK40156.1|) |
| 45. | Trypanosoma brucei (protozoan parasite; gb|AAQ56191.1|) |
| 46. | Trypanosoma cruzi (protozoan parasite; gb|ACQ66108.1|) |
| 47. | Xenopus laevis (frog; sp|O57383|DPOLB XENLA) |
| 48. | Xenopus tropicalis (western clawed frog; β-ref|NP 001006894|, λ-ref|NP 001093716.1|, μ-UniProtKB: Q5FVA7 XENTR) |
| 49. | Xiphophorus maculates (southern platyfish; gb|AAU11318.1|) |
| 50. | Yarrowia lipolytica (non-conventional yeast; λ-ref|XP 502740.1|) |
Gene identifiers are indicated in parenthesizes: ref – RefSeq (NCBI Reference Sequence Database); UniProtKB – The UniProt Knowledgebase (UniProtKB), UniProtKB/Swiss-Prot and UniProtKB/TrEMBL; NCBI GenPept, gb, gi – GenBank; emb, EMBL-EBI – European Nucleotide archive; dbj – DNA Databank of Japan; sp – Swiss-Prot; tr – TrEMBL.