Figure 4. Cediranib and quinacrine inhibit Akt activation.

Western blot analysis of basal Akt and phospho-Akt levels in 4C8 cultures grown under hypoxic (0.5% O₂) conditions for 24 hrs while untreated or exposed to cediranib (2.5 µM), quinacrine (2.5 µM), or combined cediranib/quinacrine.