Table 2. Lipid and Lipoprotein Measurements by eGFR Category.
| eGFR (mL/min/1.73 m2), All Races | P Value | eGFR (mL/min/1.73 m2), White Subjects | P Value | eGFR (mL/min/1.73 m2), Black Subjects | P Value | ||||
| >90 | 60–90 | >90 | 60–90 | >90 | 60–90 | ||||
| TC* | 173 (149–198) | 169 (146–196) | 0.07 | 169 (148–195) | 167 (145–194) | 0.25 | 176 (153–200) | 170 (151–197) | 0.22 |
| HDL-C* | 46 (37–55) | 45 (38–55) | 0.82 | 44 (36–52) | 44 (37–52) | 0.65 | 48 (41–58) | 49 (40–61) | .39 |
| LDL-C* | 98 (79–120) | 93 (77–115) | 0.02 | 94.5 (78–116) | 92 (76–113) | 0.25 | 104 (82–125) | 96 (82–116) | 0.08 |
| VLDL-C* | 24 (17–35) | 25 (17–37) | 0.44 | 26 (19–38) | 27 (18–39) | 0.61 | 20 (14–29) | 22 (15–29) | 0.71 |
| TG* | 113 (80–170) | 116 (85–170) | 0.20 | 129 (94–194) | 132 (92–187) | 0.53 | 92 (70–127) | 99 (74–128) | 0.49 |
| ApoA-I§ | 130 (116–147) | 129 (116–144) | 0.40 | 129 (114–146) | 129 (116–142) | 0.62 | 134 (120–149) | 135 (118–155) | 0.62 |
| ApoA-II§ | 34 (31–38) | 33 (30–37) | 0.02 | 34 (30–37) | 33 (30–37) | 0.22 | 34 (31–39) | 34 (30–38) | 0.15 |
| ApoB§ | 82 (70–96) | 79 (68–92) | 0.004 | 82 (72–96) | 80 (69–92) | 0.03 | 83 (70–96) | 78 (68–91) | 0.06 |
| ApoC-III§ | 10.8 (7.5–15.4) | 11.6 (8.3–15.6) | 0.04 | 12.1 (9–16.2) | 12.2 (9.2–16.2) | 0.71 | 8.75 (6.1–12.6) | 10.2 (6.8–14.2) | 0.06 |
| ApoE§ | 3.9 (3.2–4.7) | 3.8 (3.2–4.5) | 0.24 | 3.8 (3.1–4.5) | 3.7 (3.1–4.4) | 0.38 | 4.1 (3.4–4.9) | 4 (3.4–4.8) | 0.62 |
| Lp(a)* | 20 (8–51) | 20 (7–50) | 0.5 | 11 (6–28) | 12 (6–31) | 0.51 | 42 (20–76) | 49 (25–89) | 0.02 |
| FFA§ | 0.61 (0.47–0.77) | 0.62 (0.49–0.79) | 0.41 | 0.63 (0.48–0.79) | 0.63 (0.49–0.79) | 0.74 | 0.59 (0.45–0.74) | 0.62 (0.5–0.76) | 0.18 |
Data represent bivariate associations between eGFR category and each denoted lipid parameter. eGFR categories were further stratified by white and black race. Data reported as median values (IQR). P values analyzed by Wilcoxon Rank Sum test. Abbreviations: TC total cholesterol, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, VLDL-C very low density lipoprotein cholesterol, TG trigylcerides, Lp(a) lipoprotein(a), apoA-I apolipoprotein A-I, apoA-II apolipoprotein A-II, apoB apolipoprotein B, apoC-III apolipoprotein C-III, apoE apolipoprotein E, FFA free fatty acids. *N = 1852, §N = 1439