Table 5. Association Between Lower eGFR Category and Lp(a)>30 mg/dL.
Multivariable Model | Odds Ratio (95% CI) | P Value |
Model 1 | 1.33 (1.06–1.67) | 0.014 |
Model 2 | 1.34 (1.07–1.69) | 0.012 |
Model 3 | 1.36 (1.07–1.72) | 0.011 |
Model 4 | 1.35 (1.06–1.71) | 0.013 |
Data represent odds of lower eGFR category with plasma Lp(a) greater than 30 mg/dL. Logistic regression performed in incremental models with the following co-variates.
Model 1: Age, gender, race.
Model 2: Age, gender, race, BMI, hypertension, lipid-lowering medications (statin, fibrate, niacin).
Model 3: Age, gender, race, BMI, hypertension, lipid-lowering medications, hemoglobin A1c, HOMA-IR, duration on insulin.
Model 4: Age, gender, race, BMI, hypertension, lipid-lowering medications, hemoglobin A1c, HOMA-IR, duration on insulin, urinary ACR.
*Definition of hypertension includes the use of anti-hypertensive medications.