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. 2014 Dec 9;9(12):e114397. doi: 10.1371/journal.pone.0114397

Table 5. Association Between Lower eGFR Category and Lp(a)>30 mg/dL.

Multivariable Model Odds Ratio (95% CI) P Value
Model 1 1.33 (1.06–1.67) 0.014
Model 2 1.34 (1.07–1.69) 0.012
Model 3 1.36 (1.07–1.72) 0.011
Model 4 1.35 (1.06–1.71) 0.013

Data represent odds of lower eGFR category with plasma Lp(a) greater than 30 mg/dL. Logistic regression performed in incremental models with the following co-variates.

Model 1: Age, gender, race.

Model 2: Age, gender, race, BMI, hypertension, lipid-lowering medications (statin, fibrate, niacin).

Model 3: Age, gender, race, BMI, hypertension, lipid-lowering medications, hemoglobin A1c, HOMA-IR, duration on insulin.

Model 4: Age, gender, race, BMI, hypertension, lipid-lowering medications, hemoglobin A1c, HOMA-IR, duration on insulin, urinary ACR.

*Definition of hypertension includes the use of anti-hypertensive medications.